Correcting shaded illumination on medical image.

By using CLAHE algorithm, there’s some problem occurs by object shapes like this:

Each edge side of object going too darken by window leveling. It is defecting issue of CLAHE. So I tried to make it corrected with shading correction.

Here is source raw image, 14bit gray.

First, I need make a background mask to overriding changed level after CLAHE.

It can generate simply by using my librawprocessor. Then I applied CLAHE, 10×10, 30.0f.

Shadowed or shaded areas occurs after applying CLAHE, it must be corrected. So I made shaded map with my fast resize engine. Down scale to 10% of original image size with Bi-Linear filter, then up scale again with B-Spline filter with inverse.

It is much effective than Gaussian blur. Very fast but similar to Gaussian blurred. almost realtime in 3000×3000 array with floating point  levels in AVX and OpenMP optimization.

Now I am just add masked shade map level with exponential to original image.

Result is :

Shaded object areas seems to enhanced than before. So I continued to applying background mask.

Ok, then I made it to window leveled.

Each edge sides are not seems to much shaded than before. It should be better than applying single CLAHE. I will continue to write more effective image processing with CLAHE.